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Polynucleotides are rapidly becoming one of the most talked-about skin rejuvenation treatments in the aesthetic world – and for good reason.
Polynucleotides are skin treatments that stimulate collagen production, improve skin elasticity, and enhance overall skin health.
At Omniya Clinic in London, we offer advanced polynucleotide injections that help repair and regenerate the skin from within, resulting in firmer, healthier, and more radiant skin.
Polynucleotides are long chains of nucleotides, the building blocks of DNA and RNA. In aesthetic medicine, these molecules are derived from purified salmon DNA and used to stimulate cellular regeneration and repair by engaging with skin cells to produce collagen.
This treatment works by mimicking your skin’s DNA fragments to trigger natural healing and rejuvenation. The high biocompatibility of polynucleotides makes them very effective for skin health, which is why they are a popular choice for skin boosters in aesthetic treatments.
Unlike traditional fillers that simply replace lost volume, polynucleotides improve the underlying health and structure of your skin over time, making them ideal for patients who want a more natural, restorative approach to ageing.
Polynucleotides work at a deep cellular level by:
Studies show polynucleotides increase fibroblast activity, leading to enhanced production of collagen and elastin for firmer, more youthful skin.
They attract and bind water molecules within the skin’s matrix, creating a plumper, more radiant complexion.
Polynucleotides reduce inflammation and redness through their biological properties, making them suitable even for sensitive skin types.
They support optimal fibroblast growth and tissue renewal, accelerating the skin’s natural repair mechanisms.
Research indicates polynucleotides help neutralize free radicals, protecting skin from oxidative stress.
These treat multiple skin concerns simultaneously, such as fine lines, wrinkles and scarring and give natural healthy looking results. Additionally, they contribute to overall skin rejuvenation by enhancing skin health and promoting regeneration and renewal.
Polynucleotides are particularly effective in areas where the skin is thin, crepey, or prone to volume loss. Popular treatment zones include the under-eye area, cheeks, neck, décolletage, and even the scalp.
Here are some of the key advantages:
Polynucleotide treatments are for individuals looking for natural skin rejuvenation and long term skin health. Ideal candidates are those who:
Note: Polynucleotide treatments contain fish derived ingredients and are not suitable for vegetarians, vegans or individuals with fish allergies. The treatment is not recommended during pregnancy or breastfeeding.
At Omniya Clinic we create a bespoke treatment plan for each patient’s individual skin concerns. Our process is:
In our extensive experience, we expect to see improvements in skin texture and hydration immediately after treatment but the full benefits will develop over the next 60 days. Results last around 6-9 months depending on individual factors and skin concerns.
Many patients notice improvements in skin texture and hydration soon after treatment. The skin often appears more radiant and feels smoother even after the first session.
While initial results are visible quickly, the full benefits develop progressively over the next 60 days as the polynucleotides stimulate your body’s natural collagen production and cellular regeneration processes.
Results typically last around 6-9 months, depending on individual factors such as age, lifestyle, and specific skin concerns. Many of our London patients report continued improvement in skin quality even after the treatment effects have technically subsided
Our Knightsbridge clinic consistently records high satisfaction rates among polynucleotide patients, with many reporting that the treatment exceeded their expectations for natural, youthful-looking skin without an artificial appearance.
Polynucleotides offer a unique approach to skin rejuvenation. To dispel uncertainty with how they compare to other aesthetic treatments available in London:
Polynucleotides are a natural approach to skin rejuvenation compared to other aesthetic treatments. Unlike dermal fillers which add volume, polynucleotides stimulate the body’s own regenerative processes, natural looking long lasting results with minimal downtime. Perfect for those who want subtle progressive results.
| Polynucleotides | Dermal Fillers |
|---|---|
| Stimulate natural regeneration | Provide immediate volume enhancement |
| Improve overall skin quality | Create defined contours and structure |
| Results develop progressively over 2-8 weeks | Deliver almost instant visible transformation |
| Enhance natural skin appearance | Create beautiful sculpted results |
| Focus on skin quality improvement | Excel at structural enhancement |
These treatments work excellently, but address different aspects of facial ageing.
| Polynucleotides | Botox |
|---|---|
| Improve skin quality and structure | Relax muscles that cause expression lines |
| Enhance skin's moisture retention | Create a smoother, more relaxed appearance |
| Build collagen for long-term benefits | Provide quick, reliable results |
| Focus on skin texture and elasticity | Excel at treating dynamic facial expressions |
We often combine polynucleotide treatments with other aesthetic procedures:
Our practitioners will create a bespoke treatment plan for you to address your individual needs for skin rejuvenation.
The regenerative properties of polynucleotides are showing promise in addressing hair loss:
The regenerative properties of polynucleotides are showing promise in addressing under-eye concerns:
At Omniya Clinic we are constantly updating our knowledge and skills in aesthetic medicine so you get the latest and best treatments.
While Profhilo and hyaluronic acid fillers offer hydration and volume, polynucleotides go one step further by supporting tissue regeneration at a cellular level. Profhilo can be excellent for widespread hydration, but polynucleotides are often the preferred choice for delicate areas like the eyes, or where you want long-term skin improvement rather than temporary plumping.
At Omniya Clinic, we often combine polynucleotides with other injectables such as Botox or Profhilo for a tailored approach.
Ready to get glowing? Book a consultation with one of our practitioners at Omniya Clinic London today to see how polynucleotide skin boosters can work for you.
varies per patient
A polynucleotide injectable treatment is a skin boosting treatment that uses polynucleotide injections to stimulate skin regeneration, to improve skin quality and elasticity for a more radiant look.
Both polynucleotides and dermal fillers can improve the appearance of the skin, polynucleotides primarily focus on stimulating natural skin regeneration and collagen production, whereas dermal fillers are used to restore volume and fill in specific areas of the face.
Polynucleotide treatments offer a versatile solution for those seeking to smooth out fine lines and wrinkles, combat early signs of ageing, revive dehydrated skin, correct pigmentation, even out skin texture, or diminish scarring and under-eye concerns such as puffiness and dark circles. To ensure the treatment is tailored to your unique needs, a consultation with your physician is essential to identify the most suitable treatment approach for you.
For more information on whether Polynucleotides are right for you, please review our contraindications, pre- and post- treatment advice page.
The effects of each session can be seen for several months, we recommend 2 to 3 sessions over a 3-week period. We also advise maintenance treatments every 6 to 9 months.
The rejuvenating effects of polynucleotide treatments are long-lasting, with maintenance sessions recommended every 6-9 months for enduring skin health and vitality. Regular treatments can provide more noticeable and long-lasting results
Yes, the polynucleotide treatments used at Omniya Clinic are biocompatible and safe across various skin types and conditions. During your appointment, your practitioner will have a thorough consultation with you to ensure you are suitable for the treatment.
Ameela was the first to market, and it stands out due to its potent combination of PDRN Salmon DNA, purity, moisturising power, and ability to target free radicals and regenerate tissue.
Polynucleotide injections stimulate collagen production which firms the skin and improves elasticity, to address sagging skin and give it a more lifted look.
Yes, polynucleotide treatments are generally suitable for sensitive skin, but it’s always best to consult with your practitioner to tailor the treatment to your skin.
Yes. Polynucleotide injections can be used under the eyes to refresh tired eyes, reduce dark circles and fine lines for a brighter more youthful look.
Polynucleotides work well with other aesthetic treatments, like dermal fillers. They can help to harmonise the face while refining skin texture and tone.
Polynucleotide treatments support the skin’s natural cell regeneration, to improve texture, resilience and overall skin quality over time.
By stimulating collagen and elastin production polynucleotide injections smoothes out the skin, reduces fine lines and revives dull or rough skin.
Polynucleotide treatments should be performed by an experienced medical professional to get the best results and safety.
Yes, most patients can go back to their normal routine soon after treatment as polynucleotide injections have minimal downtime.
During your consultation, we will advise you on the best treatments and products to use at home.
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