3a Montpelier Street, Knightsbridge, London, SW7 1EX
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Feeling “not yourself”; flat, irritable, unmotivated or overwhelmed, is common, and it’s often treatable. Low mood can develop gradually or appear after periods of stress, illness or hormonal change.
At Omniya Clinic in Knightsbridge, our doctors take a medical, root-cause approach to understanding your symptoms. Low mood may stem from hormonal imbalance, thyroid dysfunction, nutrient deficiencies, poor sleep, chronic stress, medications, or other underlying health conditions.
Rather than simply coping, we help you understand what’s driving your mood changes and create a tailored plan to support emotional, hormonal and physical balance, so you can feel clearer, calmer and more like yourself again.
Book a confidential consultation at Omniya
Low mood refers to a persistent dip in emotional wellbeing. You may feel sad, flat, anxious, or less motivated than usual. Everyday activities might feel harder, and things you normally enjoy may bring less satisfaction.
It’s common to also experience poor sleep, brain fog, low energy, irritability, or changes in appetite. While stressful life events can contribute, ongoing low mood often points to an underlying medical or hormonal cause that can be addressed.
Hormonal changes play a significant role. In women, falling oestrogen and progesterone levels during perimenopause and menopause can affect mood-regulating neurotransmitters such as serotonin. In men, low testosterone can contribute to fatigue, irritability, and emotional flatness, often referred to as “andropause.”
At Omniya Clinic, we look at the whole picture – hormones, thyroid health, stress, sleep, nutrition and medications – to uncover why you’re feeling low and help you restore balance, clarity and motivation.
Low mood rarely has a single cause — it’s often the result of several overlapping factors. At Omniya Clinic in Knightsbridge, we look at your hormones, thyroid, nutrition, stress, sleep, and medications to understand what’s driving your symptoms and how best to treat them.
Because low mood is often multifactorial, our team takes a comprehensive, root-cause approach — combining medical assessment, targeted blood testing, and tailored treatment to help you regain clarity, motivation, and emotional stability.
Occasional dips in mood are normal, but persistent or worsening symptoms can signal an underlying issue that deserves medical attention. Watch for these signs that it’s time to book a review:
Small, consistent habits can have a big impact on mood, energy, and motivation. These evidence-based foundations help regulate hormones, stabilise mood, and support any treatment you choose to pursue.
Stabilising oestrogen/progesterone can improve sleep, vasomotor symptoms, brain fog and overall emotional steadiness in peri/menopause, often lifting mood indirectly and, for some, directly.
Not automatically. HRT is reviewed regularly and continued only if benefits outweigh risks for you. Many remain on the lowest effective dose and reassess over time.
If low testosterone is confirmed and TRT is appropriate, it may improve libido, energy and mood, and can support erectile function alongside other measures where needed.
When low testosterone is the driver: low motivation, reduced drive, irritability and brain fog may improve under supervised TRT, plus sleep and energy gains.
They can support hydration/nutrients but are an adjunct. Long-term improvement comes from addressing the underlying causes (hormones, thyroid, iron/B12, sleep, stress, metabolism).
Hormone & Fertility | 10 September 2025
Care Instructions & Suitability | 29 August 2025
During your consultation, we will advise you on the best treatments and products to use at home.
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